RISK FACTORS AND PREVALENCE OF H.PYLORI INFECTION IN DYSPEPTIC PATIENTS - A STUDY IN A TERTIARY CARE INSTITUTE IN SOUTH INDIA

Abstract


Aims: T h e a i m o f t h i s s t u d y i s t o a n a l y s e t h e r i s k f a c t o r s a s s o c i a t e d w i t h H . p y l o r i i n f e c ti o n a n d t o d e t e r mi n e t h e p r e v a l e n c e of H.Pylori infection in patients with dyspepsia and to make use of the results of this study to start Anti H.pylori regime in patients with certain analysed risk factors.

Methods and Material: 100 Patients, visiting the outpatient Department and those admitted as inpatients with complaints consistent with dyspepsia were selected at random. Informed Consent was obtained. Upper gastro intestinal endoscopy is done and patients with positive findings were biopsied according to Sydney protocol. Then the samples are sent in formalin and specimens are stained with Warthin starry silver stain and H.pylori were studied. Type of study: A prospective descriptive study.

Results: Out of 100 patients subjected to the study, 54 were H.pylori positive and 46 were H.pylori negative. Increased incidence of infection in seen in males when compared to females. Most common symptom is abdominal pain. Likewise increasing age, smoking, alcohol, unhygienic drinking water, poor sanitation, obesity were found to have positive relationship with H.pylori. Patients with endoscopically proven ulcer show high positivity when compared to other findings.

Conclusion: H.Pylori testing is done by Microscopy ,the ‘gold standard’ method for detection and stained by Warthin starry silver stain which is highly sensitive and specific. The risk factors and prevalence of H.pyori infection is studied and these results are used to start appropriate Anti- H.pylori regime, which aims at eradication of H.pylori infection.

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